2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-158776
    SLU-10482
    		Inhibitor
    SLU-10482 is an orally active anti-parasitic agent, that inhibits Cryptosporidium parvum with an IC50 of 0.0687 μM. SLU-10482 exhibits anti-infective efficacy in C. parvum infected mice with an AC50 of 0.0686 μM.
    SLU-10482
  • HY-168862
    Insecticidal agent 18
    		Inhibitor
    Insecticidal agent 18 (compound 34) is a potent insecticidal agent. Insecticidal agent 18 shows acaricidal activity.
    Insecticidal agent 18
  • HY-145287
    S-MGB-234
    S-MGB-234 is a minor groove binder of Animal African Trypanosomiasis (AAT). S-MGB-234 displays excellent in vitro activities against the principal causative organisms of AAT; Trypanosoma congolense, and Trypanosoma vivax. S-MGB-234 does not show cross-resistance with the current diamidine agents and are not internalized via the transporters used by diamidines.
    S-MGB-234
  • HY-101660
    Nifursemizone
    		Inhibitor 99.25%
    Nifursemizone is an antiprotozoal agent.
    Nifursemizone
  • HY-146487
    Anti-infective agent 1
    		Inhibitor
    Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL.
    Anti-infective agent 1
  • HY-168656
    Ac-Atovaquone
    		Inhibitor
    Ac-Atovaquone is a potent cytochrome bc1 inhibitor and also is an ester-linked acetyl derivative of atovaquone (HY-13832). Ac-Atovaquone has the potential for the research of malaria.
    Ac-Atovaquone
  • HY-163484
    ELQ-650
    		Inhibitor
    ELQ-650 is a quinolone derivative, that exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-650 attenuates babesiosis in immunosuppressed mice.
    ELQ-650
  • HY-168619
    DNA crosslinker 6
    		Inhibitor
    DNA crosslinker 6 (compound 1) is an anti-kinetoplastid compound. DNA crosslinker 6 has a strong ability to bind AT-DNA and can inhibit the binding of AT-hook 1 to DNA (IC50=0.03 µM). In addition, DNA crosslinker 6 also has antiprotozoal activity, with an EC50 value of 0.83 µM for the inhibition of T. brucei.
    DNA crosslinker 6
  • HY-B0621S1
    Triclabendazole-13C,d3
    		Inhibitor
    Triclabendazole-13C,d3 is the 13C- and deuterium labeled Triclabendazole.
    Triclabendazole-<sup>13</sup>C,d<sub>3</sub>
  • HY-N9488
    Girinimbine
    		Inhibitor
    Girinimbine (Girinimbin) is a carbazole alkaloid with a variety of biological effects. Girinimbine can induce apoptosis, and has antitrypanosomal, antiplatelet activity, antibacterial activity, anti-inflammatory, antioxidant and antitumor activities.
    Girinimbine
  • HY-A0130S
    Sulfalene-13C6
    		Inhibitor ≥99.0%
    Sulfalene-13C6 is the 13C6 labeled Sulfalene. Sulfalene (Sulfametopyrazine) is an antimalarial agent. Sulfalene is also a long-acting sulfonamide antibacterial.
    Sulfalene-13C<sub>6</sub>
  • HY-17439R
    Salinomycin sodium salt (Standard)
    Salinomycin (sodium salt) (Standard) is the analytical standard of Salinomycin (sodium salt). This product is intended for research and analytical applications. Salinomycin sodium salt (Salinomycin sodium), an antibiotic potassium ionophore, is a potent inhibitor of Wnt/β-catenin signaling. Salinomycin sodium salt (Salinomycin sodium) acts on the Wnt/Fzd/LRP complex, blocks Wnt-induced LRP6 phosphorylation, and causes degradation of the LRP6 protein. Salinomycin sodium salt (Salinomycin sodium) shows selective activity against human cancer stem cells.
    Salinomycin sodium salt (Standard)
  • HY-132906
    Antimalarial agent 3
    		Inhibitor
    Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC50 = 0.035 μM) and has a very high selectivity index with respect to mammalian cells.
    Antimalarial agent 3
  • HY-125648
    Euphorbadienol
    		Inhibitor
    Euphorbadienol (alpha-Euphorbol), a triterpenic compound, isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity.
    Euphorbadienol
  • HY-N2894
    Piperolactam A
    		Inhibitor
    Piperolactam A is a natural product that can be isolated from root of Piper betle. Piperolactam A exhibits promising leishmanicidal action against wild type and drug resistant strains of Leishmania donovani.
    Piperolactam A
  • HY-162903
    LN002
    LN002 is an orally active anti-Cryptosporidium oxidase inhibitor for the study of cryptosporidiosis.
    LN002
  • HY-B0508S1
    Ornidazole-13C2,15N2
    		Inhibitor
    Ornidazole-13C2,15N2 is the 13C, 15N labeled Ornidazole. Ornidazole (Ro 7-0207) is a nitroimidazole derivative with anti-trichomonad activity and in vitro activity against a variety of anaerobic bacteria. Ornidazole inhibits Sonic hedgehog (Shh) signaling pathway, exhibits antitumor activity. Ornidazole can be used in research of Crohn’s disease.
    Ornidazole-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N<sub>2</sub>
  • HY-132929
    TCMDC-125431
    		Modulator
    TCMDC-125431 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization.
    TCMDC-125431
  • HY-B1118S2
    Secnidazole-d4
    Secnidazole-d4 is the deuterium labeled Secnidazole. Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis.
    Secnidazole-d<sub>4</sub>
  • HY-17506AR
    Azithromycin hydrate (Standard)
    Azithromycin (hydrate) (Standard) is the analytical standard of Azithromycin (hydrate). This product is intended for research and analytical applications. Azithromycin hydrate is a macrolide antibiotic useful for the treatment of a number of bacterial infections.
    Azithromycin hydrate (Standard)
Parasite Isoform Comparison

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